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1

Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase

Monica Donghi, Barbara Attenni, Cristina Gardelli, Annalise Di Marco, Fabrizio Fiore, Claudio Giuliano, Ralph Laufer, Joseph F. Leone, Vincenzo Pucci, Michael Rowley, Frank Narjes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 467 KB

english, 2009

2

Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

Marco Ferrara, Benedetta Crescenzi, Monica Donghi, Ester Muraglia, Emanuela Nizi, Silvia Pesci, Vincenzo Summa, Cristina Gardelli

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

3

Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates

Savina Malancona, Monica Donghi, Marco Ferrara, Josè I. Martin Hernando, Marco Pompei, Silvia Pesci, Jesus M. Ontoria, Uwe Koch, Michael Rowley, Vincenzo Summa

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

4

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Summa, Vincenzo, Petrocchi, Alessia, Bonelli, Fabio, Crescenzi, Benedetta, Donghi, Monica, Ferrara, Marco, Fiore, Fabrizio, Gardelli, Cristina, Gonzalez Paz, Odalys, Hazuda, Daria J.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 262 KB

english, 2008

5

Comparison of in-hospital secondary prevention for different vascular diseases

Andreas Perren, Bernard Cerutti, Mario Lazzaro, Davide Donghi, Marco Previsdomini, Claudio Marone

Journal:

European Journal of Internal Medicine

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

6

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

Muraglia, Ester, Kinzel, Olaf, Gardelli, Cristina, Crescenzi, Benedetta, Donghi, Monica, Ferrara, Marco, Nizi, Emanuela, Orvieto, Federica, Pescatore, Giovanna, Laufer, Ralph, Gonzalez-Paz, Odalys, Di

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 375 KB

english, 2008

7

Phosphoramidate Prodrugs of 2′- C -Methylcytidine for Therapy of Hepatitis C Virus Infection

Gardelli, Cristina, Attenni, Barbara, Donghi, Monica, Meppen, Malte, Pacini, Barbara, Harper, Steven, Di Marco, Annalise, Fiore, Fabrizio, Giuliano, Claudio, Pucci, Vincenzo, Laufer, Ralph, Gennari, N

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.42 MB

english, 2009

8

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

Grieco, Michele, Santoro, Massimo, Berlingieri, Maria Teresa, Melillo, Rosa Marina, Donghi, Rosangela, Bongarzone, Italia, Pierotti, Marco A., Della Ports, Giuseppe, Fusco, Alfredo, Vecchiot, Giancarl

Journal:

Year:

1990

Language:

english

File:

PDF, 835 KB

english, 1990

9

Papillomavirus, p53 alteration and primary carcinoma of the vulva

Pilotti, Silvana, Donghi, Rosangela, D'Amato, Lucia, Giarola, Monica, Longoni, Alberto, Della Torre, Gabriella, De Palo, Giuseppe, A. Pierotti, Marco, Rilke, Franco

Journal:

European Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 223 KB

english, 1993

10

ROLE OF RIGHT VENTRICLE AND PULMONARY HYPERTENSION ON DETERMINING ΔVO2/ΔWORK RATE FLATTENING: INSIGHTS FROM CARDIOPULMONARY EXERCISE TEST COMBINED WITH EXERCISE ECHOCARDIOGRAPHY

Bandera, Francesco, Generati, Greta, Pellegrino, Marta, Donghi, Valeria, lfonzetti, Eleonora, Maddalena, Gaeta, Villani, Simona, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 193 KB

english, 2014

11

EXERCISE GAS EXCHANGE PHENOTYPES IN DIABETIC SUBJECTS: FINDINGS FROM THE EURO(PEAN) EX(ERCISE) POPULATION-BASED STUDY

Guazzi, Marco, Pellegrino, Marta, Generati, Greta, Donghi, Valeria, Alfonzetti, Eleonora, Bandera, Francesco

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

12

ECHOCARDIOGRAPHIC AND CARDIOPULMONARY PHENOTYPES RELATED TO THE SEVERITY OF FUNCTIONAL MITRAL REGURGITATION DURING MAXIMAL EXERCISE TESTING IN HEART FAILURE

Bandera, Francesco, Generati, Greta, Pellegrino, Marta, Donghi, Valeria, lfonzetti, Eleonora, Garatti, ndrea, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 197 KB

english, 2014

13

Modulation of the human Ha--1 oncogene expression by DNA methylation

Pierotti, Marco A., Borrello, Maria G., Bongarzone, Italia, R. Cattadori Rosangela Donghi, Maria, Mondellini, Piera, Traversari, Catia, Della Porta, Giuseppe

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1987

Language:

english

File:

PDF, 248 KB

english, 1987

14

Small Cell Lung Cancer (SCLC) in the left lung treated with chemotherapy and radiotherapy followed, after 5 years, by non-small lung cancer in the other lung

Giura, Raffaele, Donghi, Marco, Antonelli, Paola

Journal:

Year:

1994

Language:

english

File:

PDF, 155 KB

english, 1994

15

ASSESSING EXERCISE PERFORMANCE BY COMBINING CARDIOPULMONARY TEST TO STRESS ECHO IN AORTIC STENOSIS

Bandera, Francesco, Generati, Greta, Pellegrino, Marta, Donghi, Valeria, Alfonzetti, Eleonora, Garatti, Andrea, Castelvecchio, Serenella, Menicanti, Lorenzo, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 182 KB

english, 2014

16

Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

Harper, Steven, Ferrara, Marco, Crescenzi, Benedetta, Pompei, Marco, Palumbi, Maria Cecilia, DiMuzio, Jillian M., Donghi, Monica, Fiore, Fabrizio, Koch, Uwe, Liverton, Nigel J., Pesci, Silvia, Petrocc

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.36 MB

english, 2009

17

ASSESSING RIGHT VENTRICULAR FUNCTIONAL RESERVE DURING EXERCISE IN HEART FAILURE COMBINING CARDIOPULMONARY EXERCISE TESTING WITH EXERCISE-ECHOCARDIOGRAPHY

Generati, Greta, Bandera, Francesco, Pellegrino, Marta, Labate, Valentina, Donghi, Valeria, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 245 KB

english, 2015

18

EXERCISE GAS EXCHANGE PHENOTYPES IN A POPULATION AT RISK AND REDUCED HEART RATE RECOVERY POST-EXERCISE: FINDINGS FROM THE EURO(PEAN) EX(ERCISE) POPULATION-BASED STUDY

Pellegrino, Marta, Generati, Greta, Bandera, Francesco, Labate, Valentina, Donghi, Valeria, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 235 KB

english, 2015

19

CARDIAC DETERMINANTS OF FUNCTIONAL CAPACITY: CARDIOPULMONARY EXERCISE TESTING COMBINED WITH EXERCISE-ECHOCARDIOGRAPHY

Bandera, Francesco, Generati, Greta, Pellegrino, Marta, Labate, Valentina, Donghi, Valeria, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 238 KB

english, 2015

20

EXERCISE VENTILATORY POWER IN HEART FAILURE PATIENTS: FUNCTIONAL PHENOTYPES DEFINITION BY COMBINING CARDIOPULMONARY EXERCISE TESTING WITH STRESS ECHOCARDIOGRAPHY

Labate, Valentina, Bandera, Francesco, Generati, Greta, Pellegrino, Marta, Donghi, Valeria, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 244 KB

english, 2015

21

ASSESSMENT OF RIGHT TO LEFT VENTRICULAR INTERDEPENDENCE AT REST AND DURING EXERCISE AND ITS RELATION TO A WORSE FUNCTIONAL CAPACITY AND VENTILATORY EFFICIENCY IN HEART FAILURE

Generati, Greta, Francesco, Bandera, Pellegrino, Marta, Labate, Valentina, Donghi, Valeria, Tufaro, Vincenzo, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 728 KB

english, 2016

22

CENTRAL CARDIAC OUTPUT REDISTRIBUTION DUE TO SEVERE MITRAL REGURGITATION IN ADVANCED HEART FAILURE IS ASSOCIATED WITH A HIGHER OXYGEN PERIPHERAL EXTRACTION

Generati, Greta, Francesco, Bandera, Pellegrino, Marta, Labate, Valentina, Donghi, Valeria, Tufaro, Vincenzo, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 578 KB

english, 2016

23

INCREASED EXERCISE PERIPHERAL EXTRACTION IN GROUP 2 PULMONARY HYPERTENSION AND EXERCISE OSCILLATORY VENTILATION

Generati, Greta, Francesco, Bandera, Pellegrino, Marta, Labate, Valentina, Donghi, Valeria, Tufaro, Vincenzo, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 737 KB

english, 2016

24

BALANCING THE ROLE OF CARDIAC OUTPUT VERSUSS O2 EXTRACTION DURING MAXIMAL EXERCISE IN HEART FAILURE WITH REDUCED EJECTION FRACTION: PATHOPHYSIOLOGICAL INSIGHTS

Generati, Greta, Bandera, Francesco, Pellegrino, Marta, Labate, Valentina, Tufaro, Vincenzo, Donghi, Valeria, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 715 KB

english, 2016

25

Taql RFLP of the human tropomyosin gene (TPM3) involved in the generation of the TRK oncogene

Michieli, Paolo, Pierotti, Marco A., Benedetti, Virna De, Donghi, Rosangela, Mondini, Patrizia, Radice, Paolo, Porta, Giuseppe Della

Journal:

Nucleic Acids Research

Year:

1991

Language:

english

File:

PDF, 91 KB

english, 1991

26

Papillomavirus, p53 Alteration, and Primary Carcinoma of the Vulva

Pilotti, Silvana, D??Amato, Lucia, Torre, Gabriella Delia, Donghi, Rosangela, Longoni, Alberto, Giarola, Monica, Sampietro, Giuseppe, Palo, Giuseppe De, Pierotti, Marco A., Rilke, Franco

Journal:

Diagnostic Molecular Pathology

Year:

1995

File:

PDF, 864 KB

1995

27

HPV Detection and p53 Alteration in Squamous Cell Verrucous Malignancies of the Lower Genital Tract

Pilotti, Silvana, Donghi, Rosangela, DʼAmato, Lucia, Giarola, Monica, Longoni, Alberto, Torre, Gabriella Delia, Palo, Giuseppe De, Pierotti, Marco A., Rilke, Franco

Journal:

Diagnostic Molecular Pathology

Year:

1993

File:

PDF, 762 KB

1993

28

HPV Detection and p53 Alteration in Squamous Cell Verrucous Malignancies of the Lower Genital Tract

Pilotti, Silvana, Donghi, Rosangela, D??Amato, Lucia, Giarola, Monica, Longoni, Alberto, Torre, Gabriella Della, Palo, Giuseppe De, Pierotti, Marco A., Rilke, Franco

Journal:

Diagnostic Molecular Pathology

Year:

1993

File:

PDF, 762 KB

1993

29

HPV Detection and p53 Alteration in Squamous Cell Verrucous Malignancies of the Lower Genital Tract

Pilotti, Silvana, Donghi, Rosangela, D??Amato, Lucia, Giarola, Monica, Longoni, Alberto, Torre, Gabriella Delia, Palo, Giuseppe De, Pierotti, Marco A., Rilke, Franco

Journal:

Diagnostic Molecular Pathology

Year:

1993

File:

PDF, 762 KB

1993

30

Lung Cancer in Young Adults

Bourke, William, Milstein, David, Giura, Raffaele, Donghi, Marco, Luisetti, Maurizio, Rubin, Ami-Hai E., Smith, Lewis J.

Journal:

Year:

1992

Language:

english

File:

PDF, 5.20 MB

english, 1992

31

CARDIAC DETERMINANTS OF RIGHT VENTRICULAR PRESSURE-FLOW FESPONSE TO EXERCISE IN HEART FAILURE: A STUDY BY COMBINING CARDIOPULMONARY EXERCISE TESTING AND EXERCISE ECHOCARDIOGRAPHY

Generati, Greta, Bandera, Francesco, Pellegrino, Marta, Labate, Valentina, Donghi, Valeria, Tufaro, Vincenzo, Alfonzetti, Eleonora, Guazzi, Marco

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 353 KB

english, 2016